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Philippe de Moerloose Selected Research

Afibrinogenemia (Fibrinogen Deficiency)

1/2021Clinical phenotype, fibrinogen supplementation, and health-related quality of life in patients with afibrinogenemia.
1/2021Heterogeneity of congenital afibrinogenemia, from epidemiology to clinical consequences and management.
6/2020Pharmacology, Efficacy and Safety of a Triple-Secured Fibrinogen Concentrate in Children Less than or Equal to 12 Years with Afibrinogenaemia.
1/2019Impaired factor XIII activation in patients with congenital afibrinogenemia.
9/2016Hypodysfibrinogenemia: A novel abnormal fibrinogen associated with bleeding and thrombotic complications.
7/2016Congenital afibrinogenemia: Identification and characterization of two novel homozygous fibrinogen Aα and Bβ chain mutations in two Tunisian families.
6/2016Clinical Features and Management of Congenital Fibrinogen Deficiencies.
6/2016Laboratory and Genetic Investigation of Mutations Accounting for Congenital Fibrinogen Disorders.
9/2013Congenital fibrinogen disorders: an update.
9/2012Mutation of the translation initiation codon in FGA causes congenital afibrinogenemia.
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Philippe de Moerloose Research Topics

Disease

18Afibrinogenemia (Fibrinogen Deficiency)
01/2021 - 12/2003
14Thrombosis (Thrombus)
11/2021 - 01/2004
14Hemorrhage
11/2021 - 11/2005
10Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)
01/2017 - 01/2004
5Hemophilia A (Haemophilia)
11/2021 - 05/2006
5Venous Thrombosis (Deep-Vein Thrombosis)
10/2013 - 03/2002
5Venous Thromboembolism
09/2008 - 03/2002
4Pulmonary Embolism
04/2013 - 03/2002
4Thrombocytopenia (Thrombopenia)
01/2013 - 01/2003
3Neoplasms (Cancer)
01/2021 - 03/2002
3Inflammation (Inflammations)
01/2016 - 12/2004
3Atherosclerosis
08/2012 - 12/2004
2Infections
01/2021 - 01/2004
2Disease Progression
01/2021 - 06/2016
2Systemic Lupus Erythematosus (Libman-Sacks Disease)
01/2018 - 12/2004
2Autoimmune Diseases (Autoimmune Disease)
01/2017 - 10/2013
2Rare Diseases (Rare Disease)
09/2016 - 06/2016
2Thromboembolism
09/2013 - 03/2002
2Familial Multiple Coagulation Factor Deficiency I
02/2008 - 05/2006
2Disseminated Intravascular Coagulation
06/2006 - 01/2004
1Congenital Dysfibrinogenemia
11/2021
1Hypersensitivity (Allergy)
11/2021
1Hematuria
02/2020
1Pregnancy Complications
01/2017
1Hematoma
09/2016
1Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders)
09/2016
1Rupture
06/2016
1Bone Cysts (Bone Cyst)
06/2016
1Factor XI Deficiency (Hemophilia C)
04/2013
1Stroke (Strokes)
04/2013
1Pre-Eclampsia (Preeclampsia)
01/2013
1Hemolysis
01/2013
1Eclampsia
01/2013
1Hypertension (High Blood Pressure)
06/2012
1Coronary Artery Disease (Coronary Atherosclerosis)
06/2012
1Genetic Predisposition to Disease (Genetic Predisposition)
02/2010
1Disease Susceptibility (Diathesis)
06/2009
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
04/2008
1Atherosclerotic Plaque (Atheroma)
01/2007
1Renal Insufficiency (Renal Failure)
06/2006

Drug/Important Bio-Agent (IBA)

22Fibrinogen (Factor I)FDA Link
11/2021 - 12/2003
10Antiphospholipid AntibodiesIBA
01/2018 - 11/2002
5AntibodiesIBA
11/2021 - 01/2003
4Hemostatics (Antihemorrhagics)IBA
01/2021 - 06/2006
4FibrinIBA
09/2016 - 06/2007
4Nonsense Codon (Nonsense Mutation)IBA
03/2010 - 12/2003
3Immunoglobulin G (IgG)IBA
01/2018 - 01/2004
3AntigensIBA
06/2016 - 09/2013
3EnzymesIBA
01/2013 - 12/2004
3Proteins (Proteins, Gene)FDA Link
09/2012 - 01/2007
3AnticoagulantsIBA
02/2010 - 06/2006
3Anticardiolipin AntibodiesIBA
02/2010 - 01/2004
3fibrin fragment D (D-dimer)IBA
09/2008 - 09/2002
2Peptides (Polypeptides)IBA
01/2017 - 11/2005
2Glycine (Aminoacetic Acid)FDA LinkGeneric
04/2014 - 10/2008
2Factor V (Coagulation Factor V)IBA
02/2008 - 05/2006
2Heparin (Liquaemin)FDA LinkGeneric
12/2007 - 06/2006
2factor V LeidenIBA
04/2007 - 03/2002
2Protein CIBA
04/2007 - 01/2004
1recombinant FVIIa (rFVIIa)FDA Link
11/2021
1Factor VII (Proconvertin)IBA
11/2021
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
02/2020
1Factor XIII (Coagulation Factor XIII)IBA
01/2019
1CholesterolIBA
09/2018
1InflammasomesIBA
01/2016
1Actins (F Actin)IBA
01/2016
1Factor XI (Plasma Thromboplastin Antecedent)IBA
04/2013
1Initiator Codon (Start Codon)IBA
09/2012
1CytokinesIBA
08/2012
1omega-Chloroacetophenone (Mace)IBA
06/2012
1LDL CholesterolIBA
06/2012
1fibrinogen AalphaIBA
03/2010
1Protein Sorting Signals (Signal Peptide)IBA
03/2010
1Complement System Proteins (Complement)IBA
02/2010
1fibrinopeptides gammaIBA
10/2008
1ThrombinFDA Link
10/2008
1Glycoproteins (Glycoprotein)IBA
06/2008
1Immunoglobulins (Immunoglobulin)IBA
04/2008
1Amino AcidsFDA Link
02/2008
1LectinsIBA
02/2008
15' Untranslated Regions (5' UTR)IBA
02/2008
1Serotonin (5 Hydroxytryptamine)IBA
12/2007
1InterleukinsIBA
12/2007
1Platelet Factor 4IBA
12/2007
1AntithrombinsIBA
04/2007
1Prothrombin (Factor II)IBA
04/2007
1Protein SIBA
04/2007
1Messenger RNA (mRNA)IBA
01/2007
1CollagenIBA
01/2007
1Human Serum AlbuminFDA LinkGeneric
01/2007
1LDL Receptors (LDL Receptor)IBA
01/2007
1Aprotinin (Trasylol)FDA Link
06/2006

Therapy/Procedure

7Therapeutics
02/2020 - 06/2006
2Hemodilution
06/2006 - 06/2006
2Blood Transfusion (Blood Transfusions)
06/2006 - 01/2003
1Perioperative Care
11/2021
1Tooth Extraction (Tooth Extractions)
09/2016
1Operative Surgical Procedures
01/2015
1Bariatric Surgery
04/2013
1Gastric Bypass (Roux-en-Y Gastric Bypass)
04/2013